CHEMBL49502


SMILES N#Cc1ccccc1N1CCN(CNC(=O)c2cccc(Cl)c2)CC1
InChIKey LMFZASCXAANSLM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 354.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.47 7.74 8.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.64 5.64 5.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.64 5.84 6.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.28 8.28 8.28 ChEMBL