CHEMBL475310


SMILES CC(C)CNCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O
InChIKey DPRJMIDMOOVGCT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 488.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.3 9.3 9.3 ChEMBL
δ OPRD Human Opioid A pKi 6.42 6.42 6.42 ChEMBL
κ OPRK Human Opioid A pKi 8.1 8.1 8.1 ChEMBL
μ OPRM Human Opioid A pKi 7.58 7.58 7.58 ChEMBL
NOP OPRX Human Opioid A pKi 9.3 9.3 9.3 PDSP Ki database
δ OPRD Human Opioid A pKi 6.42 6.42 6.42 PDSP Ki database
κ OPRK Human Opioid A pKi 8.1 8.1 8.1 PDSP Ki database
μ OPRM Human Opioid A pKi 7.59 7.59 7.59 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database