CHEMBL496531


SMILES O=C1c2cc3ccccc3n2CCN1CCCCN1CCN(c2cccc(Cl)c2Cl)CC1
InChIKey DGKURWUVIVQHCD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.03 8.03 8.03 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.98 9.98 9.98 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.98 9.98 9.98 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.36 5.36 5.36 PDSP Ki database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.03 8.03 8.03 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.36 5.36 5.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database