CHEMBL501882


SMILES CN1CCN(c2ccnc(N)n2)CC1
InChIKey XEKHYAPKOUIALX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 193.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.13 8.13 8.13 ChEMBL
H4 HRH4 Human Histamine A pKi 7.51 7.51 7.51 ChEMBL
H3 HRH3 Human Histamine A pKi 7.86 7.86 7.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Rat Histamine A pEC50 6.94 6.94 6.94 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.36 7.36 7.36 ChEMBL