GPCRdb

QUERCETIN

Agent/drug
Bioactivity

QUERCETIN

SMILES	O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12
InChIKey	REFJWTPEDVJJIY-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	7
Hydrogen bond donors	5
Rotatable bonds	1
Molecular weight (Da)	302.0

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1B	ADA1B	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
β₁	ADRB1	Rat	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
β₂	ADRB2	Rat	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
δ	A0A286XTF2	Guinea pig	Opioid	A	pKi	5.00	5.00	5.00	PDSP Ki database
κ	OPRK	Human	Opioid	A	pKi	5.00	5.00	5.00	PDSP Ki database
μ	OPRM	Human	Opioid	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_5A	5HT5A	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
A₁	AA1R	Rat	Adenosine	A	pKi	5.61	5.61	5.61	ChEMBL
A₁	AA1R	Rat	Adenosine	A	pKi	8.25	8.25	8.25	Drug Central
A_2A	AA2AR	Rat	Adenosine	A	pKi	5.16	5.16	5.16	ChEMBL
A_2A	AA2AR	Rat	Adenosine	A	pKi	8.29	8.29	8.29	Drug Central

Showing 1 to 20 of 37 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CCR4	CCR4	Human	Chemokine	A	pIC50	4.00	4.66	5.00	ChEMBL
CCR4	CCR4	Human	Chemokine	A	pIC50	8.30	8.30	8.30	Drug Central
CXCR1	CXCR1	Human	Chemokine	A	pIC50	5.30	5.32	5.35	ChEMBL
CXCR1	CXCR1	Human	Chemokine	A	pIC50	8.27	8.27	8.27	Drug Central
GPR35	GPR35	Human	A orphans	A	pEC50	5.10	5.17	5.23	ChEMBL
GPR35	GPR35	Human	A orphans	A	pIC50	4.81	4.81	4.81	ChEMBL
GPR35	GPR35	Human	A orphans	A	pIC50	8.32	8.32	8.32	Drug Central
M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	4.70	5.10	5.50	ChEMBL
NPS	NPSR1	Human	Neuropeptide S	A	Potency	6.80	6.80	6.80	ChEMBL
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	4.40	4.71	5.00	ChEMBL
V₂	V2R	Human	Vasopressin and oxytocin	A	pIC50	4.40	4.80	5.20	ChEMBL
V₂	V2R	Human	Vasopressin and oxytocin	A	pIC50	8.28	8.28	8.28	Drug Central

Showing 1 to 12 of 12 entries

QUERCETIN

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.