CHEMBL508974


SMILES CCOC(=O)CNC(=O)/N=C(/N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1
InChIKey DLLWIQHESQBDLY-AREMUKBSSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 6
Rotatable bonds 14
Molecular weight (Da) 602.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pKi 5.96 5.96 5.96 ChEMBL
Y1 NPY1R Human Neuropeptide Y A pKi 9.38 9.84 10.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y1 NPY1R Human Neuropeptide Y A pIC50 8.08 9.55 10.3 ChEMBL