CHEMBL4778418


SMILES Cc1c(S(=O)(=O)N[C@H]2CCN(CCCc3noc4ccccc34)C2)sc2ccc(F)cc12
InChIKey ITUXAHIEYLTLOX-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 473.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.84 7.84 7.84 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.41 8.41 8.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.82 7.82 7.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database