CHEMBL511884


SMILES CC1C2Cc3ccc(C(N)=O)cc3C1(C)CCN2C
InChIKey QQRJMFPSTOYARH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 258.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.5 6.5 6.5 ChEMBL
κ OPRK Human Opioid A pKi 7.72 7.72 7.72 ChEMBL
μ OPRM Human Opioid A pKi 8.8 8.8 8.8 ChEMBL
δ OPRD Human Opioid A pKi 6.49 6.49 6.49 PDSP Ki database
μ OPRM Human Opioid A pKi 8.8 8.8 8.8 PDSP Ki database
κ OPRK Human Opioid A pKi 7.72 7.72 7.72 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pIC50 7.6 7.6 7.6 ChEMBL
μ OPRM Human Opioid A pEC50 7.62 7.62 7.62 ChEMBL