CHEMBL4782986


SMILES N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O
InChIKey WZKUPZOZUGSSGT-QORCZRPOSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 7
Rotatable bonds 12
Molecular weight (Da) 576.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Rat Neuropeptide FF/neuropeptide AF A pKi 7.0 7.0 7.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Rat Neuropeptide FF/neuropeptide AF A pIC50 10.0 10.0 10.0 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pEC50 5.62 5.62 5.62 ChEMBL