CHEMBL516389


SMILES O=C1N(CCNC2CCC2)CN(c2ccccc2)C12CCN(Cc1c(Cl)cccc1Cl)CC2
InChIKey MDYPWJYGLCDMIE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 486.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.43 6.43 6.43 ChEMBL
κ OPRK Human Opioid A pKi 7.54 7.54 7.54 ChEMBL
NOP OPRX Human Opioid A pKi 9.3 9.3 9.3 PDSP Ki database
δ OPRD Human Opioid A pKi 6.43 6.43 6.43 PDSP Ki database
κ OPRK Human Opioid A pKi 7.54 7.54 7.54 PDSP Ki database
μ OPRM Human Opioid A pKi 6.95 6.95 6.95 PDSP Ki database
μ OPRM Human Opioid A pKi 6.95 6.95 6.95 ChEMBL
NOP OPRX Human Opioid A pKi 9.3 9.3 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database