CHEMBL4788140


SMILES C[C@H]1CN(CC[C@H]2CC[C@H](N3C(=O)[C@H]4[C@H]5C=C[C@H](C5)[C@H]4C3=O)CC2)CCc2ccc(Cl)cc21
InChIKey MJWAVTIYFCPJPE-MJGBDJQUSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 466.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.5 6.5 6.5 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.16 8.16 8.16 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database