Chembl561123

Chemical Properties

SMILES Cn1c(N2CCOCC2)nc2c(CN3CCN(c4ccccc4)CC3)c[nH]c2c1=O
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight 408.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey BPXOVNRRDFBZBM-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.6 7.6 7.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.57 5.57 5.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 6.05 6.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.96 5.05 5.14 PDSP KiDatabase
D3 DRD3 Human Dopamine A pKi 4.57 4.57 4.57 PDSP KiDatabase