Chembl561819

Chemical Properties

SMILES CC[C@H](C1CC1)n1cc(Cl)nc(Nc2c(Cl)cc(C(F)(F)F)cc2Cl)c1=O
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight 439.0

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey RMSLHAJPCMSRAQ-GFCCVEGCSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CRF1 CRFR1 Rat Corticotropin-releasing factor B1 pIC50 8.89 8.89 8.89 ChEMBL