CHEMBL4802329


SMILES N[C@@]1(C(=O)O)[C@H](CSc2ccc(F)cc2)[C@@H](O)[C@@H]2[C@H]1[C@H]2C(=O)O
InChIKey VBZWVJXSTPCEIR-GSTJWYSLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 341.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 8.17 8.17 8.17 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.98 7.98 7.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 7.38 7.38 7.38 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 7.7 7.7 7.7 ChEMBL