CHEMBL4802948


SMILES Cc1cc(SC[C@@H]2[C@@H](N)[C@H]3[C@H](C(=O)O)[C@H]3[C@]2(N)C(=O)O)ccc1F
InChIKey NZZMAEBSZGFPBU-WVXSZGNASA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 354.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.44 7.44 7.44 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.62 7.62 7.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 6.79 6.79 6.79 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 7.34 7.34 7.34 ChEMBL