CHEMBL4802990


SMILES Cc1ccc(SC[C@@H]2[C@@H](O)[C@@H]3[C@@H]([C@H]3C(=O)O)[C@]2(N)C(=O)O)cc1C
InChIKey IJUVTLSGLODULR-MSZYXCAISA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 351.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.58 7.58 7.58 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.85 7.85 7.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 7.21 7.21 7.21 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 7.56 7.56 7.56 ChEMBL