CHEMBL4803523


SMILES N[C@@]1(C(=O)O)[C@H](CSc2cccc(F)c2)[C@@H](O)[C@@H]2[C@H]1[C@H]2C(=O)O
InChIKey NFWVZCUIJDBXKM-GSTJWYSLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 341.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.6 7.6 7.6 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.36 7.36 7.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 6.57 6.57 6.57 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 7.12 7.12 7.12 ChEMBL