CHEMBL481153


SMILES O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc21
InChIKey CJGNMVAAMQAWEF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 340.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.66 5.66 5.66 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.66 5.66 5.66 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.1 6.1 6.1 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.22 8.22 8.22 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.08 6.08 6.08 ChEMBL
H2 HRH2 Human Histamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.27 7.27 7.27 ChEMBL
H1 HRH1 Human Histamine A pKi 7.54 7.54 7.54 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.18 7.18 7.18 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.02 7.02 7.02 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.23 5.23 5.23 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
H3 HRH3 Human Histamine A pKi 5.22 5.22 5.22 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.0 7.0 7.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.03 6.03 6.03 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.7 8.7 8.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.62 5.62 5.62 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database