CHEMBL483991


SMILES CC(C)c1nccc2c1c(Sc1ccc(Cl)c(Cl)c1)c1n2CC[C@@H]1CC(=O)O
InChIKey LUZBJNWFEDHIPR-GFCCVEGCSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 434.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pKi 9.49 9.49 9.49 ChEMBL
EP1 PE2R1 Human Prostanoid A pKi 4.54 4.54 4.54 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 5.4 5.4 5.4 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 6.07 6.07 6.07 ChEMBL
DP2 PD2R2 Human Prostanoid A pKi 5.32 5.32 5.32 ChEMBL
TP TA2R Human Prostanoid A pKi 6.03 6.03 6.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pIC50 8.67 9.26 9.85 ChEMBL
TP TA2R Human Prostanoid A pIC50 5.39 5.39 5.39 ChEMBL