ramatroban


SMILES OC(=O)CCn1c2CC[C@H](Cc2c2c1cccc2)NS(=O)(=O)c1ccc(cc1)F
InChIKey LDXDSHIEDAPSSA-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 416.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 6IIU

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKd 7.0 7.0 7.0 Guide to Pharmacology
MC3 MC3R Human Melanocortin A pKd 7.3 7.3 7.3 Guide to Pharmacology
MC4 MC4R Human Melanocortin A pKd 8.5 8.5 8.5 Guide to Pharmacology
MC4 MC4R Human Melanocortin A pKi 8.5 8.5 8.5 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database