Chembl571992


SMILES CCCN(CCN1CCN(c2nccc3ccccc23)CC1)[C@H]1CCc2nc(N)sc2C1
InChIKey SNMHDHJEXUFVCO-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 450.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.65 8.65 8.65 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.57 6.57 6.57 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.65 8.65 8.65 ChEMBL
D3 DRD3 Human Dopamine A pEC50 9.09 9.15 9.28 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.94 6.94 6.94 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL