PGI2


SMILES CCCCC[C@@H](/C=C/[C@H]1[C@H](O)C[C@H]2[C@@H]1C/C(=C/CCCC(=O)O)/O2)O
InChIKey KAQKFAOMNZTLHT-OZUDYXHBSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 352.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 6.59 6.59 6.59 Guide to Pharmacology
μ OPRM Human Opioid A pKi 8.7 8.7 8.7 Guide to Pharmacology
κ OPRK Human Opioid A pKi 6.58 6.58 6.58 ChEMBL
μ OPRM Human Opioid A pKi 8.02 8.02 8.02 ChEMBL
μ OPRM Human Opioid A pKi 8.1 8.1 8.1 Drug Central
κ OPRK Human Opioid A pKi 8.18 8.18 8.18 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database