CHEMBL4856702


SMILES Fc1cccc(-c2n[nH]cc2N2CCNCC2)c1
InChIKey GEFRGFSOXCXXSZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 246.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.04 6.04 6.04 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.33 7.33 7.33 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.79 6.79 6.79 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.67 6.67 6.67 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.38 7.38 7.38 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.24 7.24 7.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.63 5.63 5.63 ChEMBL