CHEMBL5200992


SMILES CN(C(=O)CCc1ccccc1)[C@@H]1C[C@]23CCN(CC4CC4)[C@H](Cc4ccc(O)cc42)[C@]32CC[C@@H]1O2
InChIKey FHLUCGJGEKUBEX-LPOYZYTQSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 486.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.69 7.69 7.69 ChEMBL
κ OPRK Human Opioid A pKi 9.48 9.48 9.48 ChEMBL
μ OPRM Human Opioid A pKi 8.84 8.84 8.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.67 7.67 7.67 ChEMBL
κ OPRK Human Opioid A pEC50 8.0 8.0 8.0 ChEMBL
μ OPRM Human Opioid A pEC50 8.25 8.25 8.25 ChEMBL