CHEMBL4858915


SMILES CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
InChIKey RFHHXSZNNSMYFH-PEAOEFARSA-N

Chemical properties

Hydrogen bond acceptors 14
Hydrogen bond donors 20
Rotatable bonds 27
Molecular weight (Da) 1092.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y4 NPY4R Human Neuropeptide Y A pKi 8.6 8.6 8.6 ChEMBL
Y1 NPY1R Human Neuropeptide Y A pKi 6.12 6.23 6.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y4 NPY4R Human Neuropeptide Y A pEC50 6.17 6.5 6.75 ChEMBL