CHEMBL4859677


SMILES CCOc1nc2ccc(OC)cc2n1CCNC(C)=O
InChIKey MRWHUOOPUIAFSB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 277.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pKi 9.03 9.03 9.03 ChEMBL
MT1 MTR1A Human Melatonin A pKi 9.38 9.38 9.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pEC50 9.59 9.59 9.59 ChEMBL
MT1 MTR1A Human Melatonin A pEC50 9.48 9.94 10.4 ChEMBL