CHEMBL4860626


SMILES O=C1c2ccccc2S(=O)(=O)N1CCCCN1CCN(c2cccc(Cl)c2Cl)CC1
InChIKey JZZWTXIQHYXBKT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 467.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.43 6.43 6.43 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.58 5.58 5.58 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.59 5.59 5.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database