CHEMBL4862180


SMILES O=C1c2ccc(Cl)cc2CC1CCCN1CCN(c2ccccn2)CC1
InChIKey QIWDESFBOGLASL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.11 7.61 8.11 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.73 5.73 5.73 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.1 7.1 7.1 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.63 8.64 8.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database