CHEMBL4865591


SMILES O=C1CCc2cc(OCCCN3CCN(c4ccccn4)CC3)ccc2N1
InChIKey NBSPIYLVJWAETB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.73 6.73 6.73 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.19 6.21 6.23 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.5 6.52 6.54 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.69 7.71 7.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.57 5.57 5.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database