CHEMBL4870361


SMILES O=C1CCc2cc(OCCCN3CCN(c4ccccn4)CC3)ccc21
InChIKey ZKLWDLIUAFTPCZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.8 5.82 5.85 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.54 6.54 6.54 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.79 6.79 6.79 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database