CHEMBL4870374


SMILES Cc1cccc(S(=O)(=O)n2ccc3c(N4CCNCC4)nc4ccccc4c32)c1
InChIKey IPEQZSDWFQRQIF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 406.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.38 5.38 5.38 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.52 8.52 8.52 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.33 5.33 5.33 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.12 6.12 6.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.67 5.67 5.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database