CHEMBL4875600


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1cccc(F)c1
InChIKey FFKSIHLRCNTALR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 4.88 4.88 4.88 ChEMBL
H2 HRH2 Human Histamine A pKi 8.69 8.69 8.69 ChEMBL
H1 HRH1 Human Histamine A pKi 5.11 5.11 5.11 ChEMBL
H3 HRH3 Human Histamine A pKi 4.41 4.41 4.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.06 8.06 8.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.5 6.5 6.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pEC50 7.19 7.19 7.19 ChEMBL
D3 DRD3 Human Dopamine A pEC50 7.14 7.14 7.14 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.23 6.23 6.23 ChEMBL