CHEMBL4877051


SMILES COc1ccc(-c2n[nH]cc2N2CCNCC2)cc1
InChIKey LOGYUXUBXWIFBI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 258.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.99 5.99 5.99 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.31 7.31 7.31 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.88 5.88 5.88 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.4 5.4 5.4 ChEMBL