CHEMBL5272486
SMILES | CN(C)CC1CN(C(=O)Cc2ccc(F)cc2)CCC1(O)c1cccc(O)c1 |
InChIKey | GRWAVFOCRMSSTA-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 2 |
Rotatable bonds | 5 |
Molecular weight (Da) | 386.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
μ | OPRM | Mouse | Opioid | A | pKi | 7.06 | 7.06 | 7.06 | ChEMBL |
δ | OPRD | Human | Opioid | A | pKi | 6.87 | 6.87 | 6.87 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 7.38 | 7.38 | 7.38 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
δ | OPRD | Human | Opioid | A | pEC50 | 6.11 | 6.11 | 6.11 | ChEMBL |
μ | OPRM | Human | Opioid | A | pEC50 | 8.19 | 8.19 | 8.19 | ChEMBL |