CHEMBL5273356


SMILES CN(C)CC1CN(C(=O)Cc2cc(F)c(F)cc2F)CCC1(O)c1cccc(O)c1
InChIKey JMDFENKDWRFUQU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 422.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 8.7 8.7 8.7 ChEMBL
δ OPRD Human Opioid A pKi 6.41 6.41 6.41 ChEMBL
κ OPRK Human Opioid A pKi 7.19 7.19 7.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 6.35 6.35 6.35 ChEMBL
κ OPRK Human Opioid A pEC50 7.12 7.12 7.12 ChEMBL
μ OPRM Human Opioid A pEC50 7.24 7.24 7.24 ChEMBL