CHEMBL552373


SMILES N#Cc1cccc(N2CCN(CCN3CCC(C(F)(F)F)CC3)C2=O)c1
InChIKey ZULQKQGLUORZDC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.64 6.64 6.64 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.57 6.57 6.57 ChEMBL
D3 DRD3 Rat Dopamine A pKi 9.1 9.1 9.1 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.77 6.77 6.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.0 9.12 9.29 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.8 6.98 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database