CHEMBL492639


SMILES CCO/N=C/c1ccccc1OC(C)C1=NCCN1
InChIKey BVWLLEDYRCHASI-LICLKQGHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 261.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.35 6.35 6.35 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.47 6.47 6.47 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 6.0 6.0 6.0 ChEMBL