CHEMBL493272


SMILES c1ccc(-c2cccc3c2OCC(C2=NCCN2)O3)cc1
InChIKey MQSPJCMZCOHHPI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 280.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.97 5.97 5.97 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.08 6.08 6.08 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.14 6.14 6.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 4.9 4.9 4.9 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 6.1 6.1 6.1 ChEMBL