CHEMBL493331


SMILES C[C@H]1CN(Cc2cccc(-c3cc(CNC(=O)c4cccc(CN5CC[N+](C)(C)CC5)c4)ccc3F)c2)CCN1
InChIKey NXGNXTJVCQAXEF-VWLOTQADSA-O

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 544.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKd 9.8 9.8 9.8 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 7.9 7.9 7.9 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKd 8.7 8.7 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database