Chembl599635


SMILES CCCN(CCN1CCN(c2ccnc3c(O)cccc23)CC1)C1CCc2ccc(O)cc2C1
InChIKey XNAZWCRZSGGAMO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 460.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.9 9.0 9.09 ChEMBL
D3 DRD3 Human Dopamine A pEC50 9.13 9.13 9.13 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.8 8.07 8.34 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.77 8.77 8.77 ChEMBL