CHEMBL494991


SMILES COc1ccc(CN2CCN(CCOc3cccc4nc(C)ccc34)CC2)cc1
InChIKey JASGQPKQLWYLDV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.9 7.9 7.9 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.3 7.8 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database