CHEMBL561123


SMILES Cn1c(N2CCOCC2)nc2c(CN3CCN(c4ccccc4)CC3)c[nH]c2c1=O
InChIKey BPXOVNRRDFBZBM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.6 7.6 7.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.57 5.57 5.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 6.05 6.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 6.05 6.14 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.57 5.57 5.57 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database