CHEMBL495572


SMILES Clc1cccc(N2CCN(CCCCCOc3cc4ccccc4cn3)CC2)c1Cl
InChIKey KPLQQMQZQUMPCN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 443.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.15 5.15 5.15 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.85 9.85 9.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.85 9.85 9.85 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.15 5.15 5.15 PDSP Ki database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.74 7.74 7.74 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 7.12 7.12 7.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database