CHEMBL563614


SMILES COc1ccccc1N1CCN(Cc2c(C)nc3cc(C)nc(C)n23)CC1
InChIKey LYHPSWFRVIYURV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.08 5.08 5.08 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.85 7.85 7.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.47 5.47 5.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.54 5.59 5.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.54 5.59 5.64 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.47 5.47 5.47 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database