CHEMBL5028512


SMILES CC(=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NCCN1CCN(CCC(=O)NC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey ZYIJZBYORMBFMV-LJDVJVEBSA-N

Chemical properties

Hydrogen bond acceptors 13
Hydrogen bond donors 10
Rotatable bonds 23
Molecular weight (Da) 930.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.24 5.24 5.24 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.39 7.39 7.39 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 4.98 4.98 4.98 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.03 9.03 9.03 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.22 7.22 7.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database