CHEMBL557547


SMILES Cc1cc2c3c(c1)-c1c(ccc(O)c1O)C[C@H]3N(C)CC2
InChIKey QRJZCXSRTBCYIW-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 281.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.4 7.4 7.4 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.68 7.68 7.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pIC50 7.08 7.08 7.08 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 7.37 7.37 7.37 ChEMBL
D2 DRD2 Rat Dopamine A pEC50 7.37 7.37 7.37 ChEMBL