CHEMBL512414


SMILES NC(=O)C1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl
InChIKey XXHBZSGXGMJSEC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 464.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.77 8.77 8.77 ChEMBL
δ OPRD Human Opioid A pKi 5.63 5.63 5.63 ChEMBL
κ OPRK Human Opioid A pKi 6.57 6.57 6.57 ChEMBL
μ OPRM Human Opioid A pKi 7.42 7.42 7.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 8.22 8.22 8.22 ChEMBL
μ OPRM Human Opioid A pEC50 6.42 6.42 6.42 ChEMBL