CHEMBL56695


SMILES NC(=O)c1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314
InChIKey QAICPHMNUHNDMC-WUHBCXKYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 368.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.66 7.66 7.66 ChEMBL
δ OPRD Human Opioid A pKi 6.26 6.54 6.96 ChEMBL
κ OPRK Human Opioid A pKi 7.96 8.45 9.44 ChEMBL
μ OPRM Human Opioid A pKi 9.15 9.15 9.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 8.31 8.31 8.31 ChEMBL
μ OPRM Human Opioid A pIC50 6.57 6.57 6.57 ChEMBL