CHEMBL5195241


SMILES COc1cc2c(cc1OC)-c1c(OC)c(OCc3ccc(Br)cc3)cc3c1[C@H](C2)N(C)CC3
InChIKey RWKDELNCCMATRB-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 509.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 5.52 5.52 5.52 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.36 6.36 6.36 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.79 6.79 6.79 ChEMBL