Chembl76573


SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1CNCC(C)(C)C
InChIKey LSZXSXIVNDQCSM-URXFXBBRSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 423.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 9.0 9.0 9.0 ChEMBL
δ OPRD Human Opioid A pEC50 8.55 8.55 8.55 ChEMBL
κ OPRK Human Opioid A pIC50 8.82 8.82 8.82 ChEMBL
κ OPRK Human Opioid A pEC50 8.85 8.85 8.85 ChEMBL
μ OPRM Human Opioid A pIC50 8.89 8.89 8.89 ChEMBL